Symposium

Metabolism-based Cancer Therapy Symposium 2024

Online

In the last decade cancer metabolism has emerged as a cancer hallmark. Although it has been almost a century since Otto Warburg described a difference in cellular metabolism in cancer cells, cancer-specific metabolic alterations have not been fully exploited therapeutically. Increasing numbers of studies showed both the complexity and the promise of targeting metabolism as a therapeutic strategy in cancer. It is time for scientists and clinicians working on this strategy to meet and exchange their experience.

With a translational focus, the symposium brings together oncologists and researchers interested in exploiting the metabolic bias of tumors for therapeutic interventions. It aims to shed light and bring to discussion novel translational approaches that are either currently under clinical testing or show translational potential in preclinical studies.  

The event will be held in English.

Welcome

In the last decade cancer metabolism has emerged as a cancer hallmark. Although it has been almost a century since Otto Warburg described a difference in cellular metabolism in cancer cells, cancer-specific metabolic alterations have not been fully exploited therapeutically. Increasing numbers of studies showed both the complexity and the promise of targeting metabolism as a therapeutic strategy in cancer. It is time for scientists and clinicians working on this strategy to meet and exchange their experience.

With a translational focus, the symposium brings together oncologists and researchers interested in exploiting the metabolic bias of tumors for therapeutic interventions. It aims to shed light and bring to discussion novel translational approaches that are either currently under clinical testing or show translational potential in preclinical studies.  

Regards

Dr. med. Ekaterina Balaian
Prof. Martin Bornhäuser
Prof. Dr. med. Triantafyllos Chavakis
Dr. Mohamed Elgendy
Prof. Dr. Leoni Kunz-Schughart

Location

Online via Zoom

Registration

Please register via the link. Thank you very much!

We are looking forward to your participation!
 
Continuing Medical Education Credits (CME)
The CME credits have been applied for at the Saxon State Medical Association. We expect approx. 4 continuing medical education credits.

Program

12:00 a.m – 12:20 a.m. CET
Welcome and Opening Remarks
Ekaterina Balaian, Dresden, Germany
Mohamed Elgendy, Dresden, Germany

 

Session 1: Metabolism and its impact on metastasis and the tumor microenvironment

12:20 – 12:40 p.m. CET
Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment
Massimiliano Mazzone, Leuven, Belgium

12:50 – 1:10 p.m. CET
Spatial metabolomics or lipidomics
Johann Swinnen, Leuven, Belgium

1:20 - 1:40 p.m. CET: Break

 

Session 2: Innovative technologies in cancer metabolism and biomarker discovery

1:40 – 2:00 p.m. CET
Targeting mitochondria and glutamine pathway in myeloid malignancies
Natalia Baran, Houston, USA

2:10 – 2:30 p.m. CET
Leveraging AI/ML for Deep Dive Metabolomics in Biomarker Disscovery
Facundo Fernández, Atlanta, USA

2:40 – 3:00 p.m. CET: Break

 

Session 3: Immunometabolism: From inflammation control to CAR/T cell therapy

3:00 – 3:20 p.m. CET
Metabolic checkpoints controlling onset and resolution of inflammation
Gerhard Krönke, Berlin, Germany

3:30 – 3:50 p.m. CET
Reprogramming of immunometabolism of CAR/T cells
Camille Bigenwald, Villejuif Cedex, France

4:00 – 4:15 p.m. CET
Concluding remarks, outlook, sponsor acknowledgment and Closing
Ekaterina Balaian, Dresden, Germany
Mohamed Elgendy, Dresden, Germany

Scientific direction

Dr. med. Ekaterina Balaian, Medical Clinic 1, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden

Prof. Dr. Leoni Kunz-Schughart, OncoRay - National Center of Radiation Research in Oncology, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden

Prof. Martin Bornhäuser, Medical Clinic 1, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden

Dr. Mohamed Elgendy, Institute for Clinical Chemistry, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden

Prof. Dr. med. Triantafyllos Chavakis, Institute for Clinical Chemistry, University Hospital Carl Gustav Carus Dresden, Technische Universität Dresden

Speakers

 
Natalia Baran
Assistant Professor in the Department of Leukemia
 
MD Anderson Cancer Center, Department of Leukemia Immunometabolism
13900 Katy Freeway, Texas 77079, Houston, USA
 
Camille Bigenwald
Assistant Professor
 
Institut de Cancérologie Gustave Roussy, Gustave Roussy Tumour immunology and immunotherapy
114, rue Edouard-Vaillant, 94 805 Villejuif Cedex, France
 
Facundo Fernandez
Regents' Professor
 
Georgia Institute of Technology, School of Chemistry and Biochemistry
ES&T L1244, 901 Atlantic Drive, 901 Atlantic Drive, Atlanta, GA 30332, USA
Prof. Dr.
Gerhard Krönke
Director of the Clinic for Rheumatology and Clinical Immunology
 
Charité – Universitätsmedizin Berlin Medizinischen Klinik mit Schwerpunkt Rheumatologie und Klinische Immunologie
Charité Mitte, Charitépl. 1, 10117 Berlin, Germany
 
Massimiliano Mazzone
Professor at the Department of Oncology
 
VIB Center for Cancer Biology, Department of Oncology, University of Leuven, Campus Gasthuisberg
Herestraat 49, box 912, 3000 Leuven, Belgium
 
Johannes Swinnen
Head of the Laboratory of Lipid Metabolism and Cancer
 
KU Leuven, Laboratory of Lipid Metabolism and Cancer
ON5 Herestraat 49 - box 825, 3000 Leuven, Belgium

Sponsor

Novartis Pharma GmbH (2.000,00 €)

WE THANK OUR SPONSOR FOR THEIR KIND SUPPORT!

An event of the GWT-TUD GmbH

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