COMPERA registry
comparison of mortality rates of PH patients with Covid-19

COMPERA is the world's largest pulmonary hypertension (PH) registry. Since its launch in 2007, the registry has collected data from more than 11,000 patients with all forms of PH, and since the onset of the Covid-19 pandemic, it has also prospectively collected information on the incidence of infection. Recently, a publication from COMPERA was published in the European Respiratory Journal (ERJ), the leading international pneumology journal.

The evaluation of two time periods (Jan. 1, 2020-Dec. 31, 2021 and Jan. 1-Oct. 31, 2022) compared mortality rates of PH patients with Covid-19. Jan. 1, 2022, was chosen as the cutoff date for the comparison, as the Omicron BA.1/2 and later BA.4/5 variants were predominant in Europe as of that date. The evaluation showed that the annual rate of fatal courses fell from 20.1% in the earlier period to 1.6% in the second period, although infection rates were known to be much higher under Omicron. This is a reassuring development for both patients and scientists.

The COMPERA registry has resulted in more than 20 publications in high-impact scientific journals to date. We will keep you informed about new publications, also on our homepage.

For more information, visit

Publication: Schmidt K-H, Milger K, Pausch C, et al. Trends in COVID-19-associated mortality in patients with pulmonary hypertension: a COMPERA analysis. Eur Respir J 2023; 61: 2202440 [DOI: 10.1183/13993003.02440-2022].

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