Innovation Center Prof. Dr. phil. Dirk Lindemann

Retrovirology

The Innovation Center's research focuses on the deciphering of molecular and cellular mechanisms of the replication strategy of retroviruses as well as the development and application of retroviral vector systems for gene therapy treatment approaches. The main research object is spuma or foamy viruses, which represent a special genus with special properties within the family of retroviruses.

portait of Dirk Lindemann

DIRECTOR

Prof. Dr. phil. Dirk Lindemann

Dresden University of Technology
Medical Faculty
Institute for Medical Microbiology and Virology
Medical-Theoretical Center (MTZ)
Fiedlerstraße 42
01307 Dresden

Short Vita

Professional background:

  • since 2008: Professor of Molecular Virology, Institute of Virology, Faculty of Medicine, TU Dresden
  • 2002-2008: Group Leader, Institute of Virology, Faculty of Medicine, TU Dresden
  • 1998-2002: Group Leader at the Institute of Virology and Immunobiology, University of Würzburg, Germany
  • 1996-1997: Postdoctoral researcher at the Institute of Virology and Immunobiology, University of Würzburg, Germany
  • 1993-1996: Postdoctoral researcher at the Whitehead Institute for Biomedical Research, Cambridge, USA
  • 1992: PhD in Cell Biology, University of Basel, Switzerland

Research and development

  • Analysis of viral and cellular protein interaction during particle morphogenesis and virus entry.
  • Interaction of retroviruses with the innate immune system.
  • Functional analysis of viral capsids and glycoproteins and their role in infection and particle release.
  • Development of novel retroviral vector systems.
  • Development and application of viral transfer systems for genome editing tools.

Expertise

  • Retrovirology
  • Retroviral vector systems for gene therapy
  • Molecular virology
  • Genome editing tools
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