Innovation Center Prof. Dr. med. Stefan Bornstein

Endocrinology and metabolic medicine

The Innovation Center for the Development of New Diagnostic and Therapeutic Approaches in Endocrinology and Metabolic Medicine is concerned with defining basic mechanisms and clinical implications of cellular crosstalk in endocrine tissues. The components and mechanisms of this cellular crosstalk are studied in a comprehensive manner by defining the receptors, signaling pathways, transcription factors and gene expression profiles involved.

portait of Prof. Dr. Stefan R. Bornstein


Prof. Dr. med. Stefan Bornstein

University Hospital Carl Gustav Carus at the Technical University of Dresden

Center for Internal Medicine
Medical Clinic and Polyclinic III
House 27, 1st floor
Fetscherstraße 74
01307 Dresden

Short vita

  • 1988: Promotion an der Universität Ulm  
  • 1988-1994: Assistenzarzt und Stipendiat an der Klinik für Innere Medizin, Universität Ulm  
  • 1994-1997: Oberarzt an der Klinik für Innere Medizin, Universität Leipzig  
  • 1996-1999: Heisenberg-Stipendium der Deutschen Forschungsgemeinschaft (DFG)  
  • 1997-2001: Forschungsstipendiat und Abteilungsleiter an der Endocrine Branch, NICHD, National Institutes of Health, Bethesda, USA  
  • 2001-2004: Professor und stellvertretender Lehrstuhlinhaber an der Klinik für Endokrinologie und Stoffwechsel, Universität Düsseldorf  
  • 2004: Direktor der Medizinischen Klinik III, Universitätsklinikum Dresden

Research and development

Based on our previous findings, we have applied integrated approaches with a broad range of techniques in both research areas. This is a logical consequence of our previous work and a transfer of basic research to clinical medicine. The following questions are being investigated:

  • How does cellular crosstalk translate into differential intercellular signaling, transcriptional regulation, and gene expression?
  • How is cellular crosstalk reflected in the developmental process? What can we learn from transgenic animal models?
  • New therapeutic strategies based on a comprehensive understanding of this form of integrative medicine.


  • Internal medicine 
  • Endocrinology and metabolism 
  • Cell and gene therapies 
  • Apheresis 
  • Crosstalk to tumors and infections 
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